![]() The commonly accepted role for hemoglobin F is limited to facilitating diffusion through the placenta. In foetal circulation, however, at a partial oxygen pressure (pO2) of 25 mmHg in the umbilical vein, the oxygen carrier is type F hemoglobin which has a high oxygen affinity. Hemoglobin with decreased affinity for oxygen increases the oxygenation of tissues, because it gives up oxygen more easily during microcirculation. ![]() This process occurs mainly due to the increased synthesis of 2,3-diphosphoglycerate (2,3-DPG) in the erythrocytes, as well as through the Bohr effect. One of the basic mechanisms of adapting to hypoxemia is a decrease in the affinity of hemoglobin for oxygen. ![]() Kwasiborski, Przemysław Jerzy Kowalczyk, Paweł Zieliński, Jakub Przybylski, Jacek Cwetsch, Andrzej ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |